Family: Reuben Isham / Mary Sowle (F86841)
 | Isaac Isham, Jr. (1751-1818) 
|
 | Faith Watrous (1759-1839) |
| Elizabeth Isham (1781-1839)  |
| Mary (Polly) Isham (1784- ) |
| John Wesley Isham (1786- ) |
| Sophia Isham (1789-1842) |
| Henry Isham (1795-1871) |
| Sarah Trumbell Isham (1801-1848) |
| Reuben Isham (1781-1863)
|
| Mary Sowle (1782-1847) |
| William Isham (1800- ) |
| Mary Isham (1800- ) |
| Epaphras Isham (1802- ) |
| Epaphrus Isham (1803- ) |
| Elizabeth Isham (1804-1884) |
| Noah Isham (1807- ) |
| Philander Isham (1813-1888) |
| John Edward Isham (1819- ) |
| Diana Isham (1821- ) |
| Susan Isham (1831- ) |